Lady's Day Out Casserole Recipe

This delicious and easy casserole is a fantastic make-ahead recipe, perfect for busy weeknights or entertaining! From our 'out-of-our-league' cookbook, this crowd-pleasing dish features layers of cheesy pasta, savory meat sauce, and tender vegetables. Partially prepare it ahead of time and freeze for later, making it ideal for meal prepping. Get ready for rave reviews!

Prep Time 30 mins

Cook Time 85 mins

Calories 528.6 kcal

Protein 58g

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Recipe Author

The Forktionary Kitchen Team

Adapted from Food.com, then tested & standardized by Forktionary.

Ingredients for Lady's Day Out Casserole

1 pound macaroni
1 pound ground beef
1 medium onion, chopped
2 cloves garlic, minced
1 teaspoon black pepper
2 (24 ounce) jars spaghetti sauce
1 (28 ounce) can crushed tomatoes
2 cups shredded mozzarella cheese

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How to Make Lady's Day Out Casserole

Preheat oven to 350°F (175°C).
Cook 1 pound of macaroni according to package directions; drain well.
In a large skillet, brown 1 pound ground beef over medium-high heat. Add 1 medium onion, chopped, and 2 cloves garlic, minced, and cook until softened, about 5 minutes.
Stir in 1 teaspoon black pepper, 2 (24 ounce) jars of your favorite spaghetti sauce, and 1 (28 ounce) can of crushed tomatoes.
Bring to a simmer and cook for 20 minutes, stirring occasionally.
Grease a 2 ½-quart casserole dish.
Place half of the cooked macaroni in the prepared casserole dish.
Top with half of the meat mixture, then half of 2 cups shredded mozzarella cheese.
Repeat layers with remaining macaroni, meat mixture, and cheese.
Bake uncovered for 45 minutes, or until heated through and bubbly.

Nutrition Information (Approximate per serving)

Sodium

25 g

Sugar

35g

Fat

69g

Carbs

13g

Recipe Categories (Choose a category and find related recipes!)

Main Courses Main Dish / Dinner Beef & Red Meat Ground Beef Recipes European Italian The Americas American Southern Fall Recipes Baking

Recipe Tags (Choose a tag and find related recipes!)

Time To Make Course Main Ingredient Preparation Main Dish Beef Pasta Easy One Dish Meal Ground Beef Meat Pasta Rice And Grains 4 Hours Or Less

Frequently Asked Questions

How long does it take to make Lady's Day Out Casserole?

Lady's Day Out Casserole takes about 115 minutes from start to finish — roughly 30 minutes to prepare and 85 minutes to cook.

How many calories are in Lady's Day Out Casserole?

Lady's Day Out Casserole has approximately 528.6 calories per serving, with about 58 g protein, 13 g carbohydrates and 43 g fat.

What ingredients do I need for Lady's Day Out Casserole?

The key ingredients for Lady's Day Out Casserole are Macaroni, Ground Round, Onions, Garlic, Pepper, Pasta Sauce With Mushrooms. See the full list with measurements above.