Turkey Tetrazzini Casserole Recipe

This creamy, comforting Turkey Tetrazzini Casserole is the perfect make-ahead dish! A delicious way to use up leftover Thanksgiving turkey, this recipe is easily adaptable for individual portions, family gatherings, or large parties. Get ready for a flavor explosion of tender turkey, creamy sauce, and perfectly cooked linguine, topped with a crispy breadcrumb topping. Perfect for busy weeknights or holiday entertaining!

Prep Time 30 mins
Cook Time 105 mins
Calories 530.3 kcal
Protein 64g
Rating 3.6 (5 Reviews)
Turkey Tetrazzini Casserole 28

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Recipe Author

Chef Forktionary, author of this recipe

Recipe adapted from Food.com. Standardized by Forktionary.

Ingredients for Turkey Tetrazzini Casserole

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How to Make Turkey Tetrazzini Casserole

  1. Preheat oven to 400°F (200°C).
  2. Cook 1 pound linguine according to package directions, about 8-10 minutes. Rinse under cold water and drain thoroughly.
  3. In a large bowl, combine cooked linguine, 2 cups cooked turkey (diced), 1 (10.75 ounce) can condensed cream of mushroom soup, 1/2 cup milk, 1/4 cup grated Parmesan cheese, 1/4 teaspoon salt, and 1/4 teaspoon black pepper.
  4. **Choose your pan size:** Divide the mixture equally among individual oven-safe dishes (approximately 8 ounces each), a 9x13 inch baking dish, or a larger roasting pan.
  5. **Make the breadcrumb topping:** Melt 1/4 cup butter in a skillet over medium heat. Stir in 1 cup breadcrumbs until golden brown and toasted, about 3-5 minutes.
  6. Remove from heat and stir in 1/4 cup grated Parmesan cheese.
  7. Sprinkle the breadcrumb topping evenly over the casserole(s).
  8. **For freezing (optional):** Cover the casserole(s) tightly with foil and freeze for up to 3 months. Thaw completely in the refrigerator before baking.
  9. **Baking:** If frozen, bake covered for 1 hour and 15 minutes. If not frozen, bake uncovered for 45-60 minutes, or until heated through and bubbly. Individual portions may take slightly less time; family and larger sizes may take slightly longer. Internal temperature should reach 165°F (74°C).

Nutrition Information (Approximate per serving)

Sodium

39 g

Sugar

12g

Fat

52g

Carbs

15g