Artichoke Pasta Casserole Recipe

This easy and tasty Artichoke Pasta Casserole is a guaranteed crowd-pleaser! Creamy, cheesy, and bursting with the flavors of artichoke hearts, mushrooms, and herbs, this comforting dish is perfect for a weeknight dinner or a casual get-together. Get ready to enjoy a delicious meal in under an hour!

Prep Time 20 mins
Cook Time 45 mins
Calories 505.6 kcal
Protein 32g
Rating 4.7 (6 Reviews)
Artichoke Pasta Casserole 58

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Recipe Author

Chef Forktionary, author of this recipe

Passionate home cook & Forktionary contributor.

Ingredients for Artichoke Pasta Casserole

  • Pasta Shells
  • 14 ounces canned artichoke hearts (drained)
  • 2 tablespoons butter
  • Mushroom
  • Red Onion
  • 1 cup grated Parmesan cheese
  • 1/2 cup sour cream
  • 1/4 cup mayonnaise
  • 1/4 cup dry white wine
  • Oregano Leaves
  • Seasoning Salt
  • Paprika
  • Pepper
  • Garlic Powder
  • Tomatoes

How to Make Artichoke Pasta Casserole

  1. Cook 1 pound pasta according to package directions.
  2. Rinse the cooked pasta under cold water and drain thoroughly.
  3. While the pasta cooks, sauté 8 ounces of sliced mushrooms and 1/2 cup chopped onion in 2 tablespoons of butter until softened. Set aside.
  4. In a large bowl, combine the cooked pasta, 14 ounces of canned artichoke hearts (drained), the mushroom mixture, 1 cup grated Parmesan cheese, 1/2 cup sour cream, 1/4 cup mayonnaise, 1/4 cup dry white wine, 1 teaspoon dried oregano, 1/2 teaspoon garlic powder, and salt and pepper to taste.
  5. Pour the mixture into a greased 9x13 inch casserole dish.
  6. Top with 1 cup sliced fresh tomatoes.
  7. Bake in a preheated oven at 350°F (175°C) for 25-30 minutes, or until heated through and bubbly.
  8. Garnish with fresh oregano before serving (optional).

Chef's Tip for Extra Flavor

Chef's secret: layers of flavor make a dish truly memorable! Consider what a little extra something could bring – perhaps a touch of acidity like a good vinegar or citrus zest, a hint of smokiness from paprika, a bit of umami from mushrooms or soy sauce, or a sprinkle of toasted nuts for texture. Experiment and taste as you go!

Nutrition Information (Approximate per serving)

Sodium

18 g

Sugar

28g

Fat

43g

Carbs

21g