John's Italian Meatloaf Recipe

This mouthwatering Italian meatloaf recipe, inspired by a Southern fundraising cookbook, puts a delicious twist on a classic! Pepperoni and cheese add a burst of flavor, while the optional garlic bologna elevates it to a whole new level of deliciousness. Get ready for a comforting, flavorful meal the whole family will crave!

Prep Time 20 mins

Cook Time 75 mins

Calories 496.6 kcal

Protein 63g

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The Forktionary Kitchen Team

Adapted from Food.com, then tested & standardized by Forktionary.

Ingredients for John's Italian Meatloaf

1.5 lbs ground beef
Butter
1 medium onion, finely chopped
2 cloves garlic, minced
Green Pepper
2 large eggs
1 cup breadcrumbs
Tomato Paste
Honey
Salt And Pepper
1/2 cup sliced pepperoni
Mozzarella Cheese

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How to Make John's Italian Meatloaf

Preheat oven to 375°F (190°C).
In a large bowl, gently combine ground beef, ground pork, breadcrumbs, eggs, milk, onion, garlic, oregano, basil, salt, and pepper.
Stir in the pepperoni slices and shredded mozzarella cheese.
Shape the meat mixture into a loaf and place it in a greased 9x5 inch loaf pan.
Bake for 60-75 minutes, or until the internal temperature reaches 160°F (71°C).
Let the meatloaf rest for 10 minutes before slicing and serving. Enjoy!

Nutrition Information (Approximate per serving)

Sodium

40 g

Sugar

26g

Fat

67g

Carbs

Recipe Categories (Choose a category and find related recipes!)

Main Courses Main Dish / Dinner Beef & Red Meat Ground Beef Recipes Pork Recipes European Italian The Americas American Southern Game Day Recipes

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Frequently Asked Questions

How long does it take to make John's Italian Meatloaf?

John's Italian Meatloaf takes about 95 minutes from start to finish — roughly 20 minutes to prepare and 75 minutes to cook.

How many calories are in John's Italian Meatloaf?

John's Italian Meatloaf has approximately 496.6 calories per serving, with about 63 g protein, 7 g carbohydrates and 46 g fat.

What ingredients do I need for John's Italian Meatloaf?

The key ingredients for John's Italian Meatloaf are Ground Beef, Butter, Onion, Garlic, Green Pepper, Eggs. See the full list with measurements above.