3 Cheese Chicken Penne Recipe

A creamy, cheesy, and flavorful twist on a classic! This 3 Cheese Chicken Penne recipe is inspired by Applebee's, but elevated for your home kitchen. Enjoy tender chicken, perfectly cooked penne pasta, and a rich three-cheese alfredo sauce – all ready in under an hour! Use pre-cooked chicken for a truly speedy weeknight meal, or marinate your own for extra flavor. This recipe is easily customizable to your taste; feel free to add your favorite vegetables or spices.

Prep Time 20 mins
Cook Time 70 mins
Calories 618.2 kcal
Protein 81g
Rating 4.0 (1 Reviews)
3 Cheese Chicken Penne 50

Recipe Actions

Share this recipe:

Recipe Author

Chef Forktionary, author of this recipe

Passionate home cook & Forktionary contributor.

Ingredients for 3 Cheese Chicken Penne

  • Fresh Basil Leaf
  • Roma Tomatoes
  • Garlic Clove
  • Salt
  • 1 teaspoon olive oil (for marinade) + 2 teaspoons olive oil (for vegetables)
  • Chicken Breast
  • 2 teaspoons lemon juice
  • Italian Spices
  • Button Mushrooms
  • Purple Onion
  • Roasted Garlic Alfredo Sauce
  • Provolone Cheese
  • Parmesan Cheese
  • Mozzarella Cheese
  • Penne Pasta

How to Make 3 Cheese Chicken Penne

  1. Marinate chicken: In a bowl, whisk together 2 teaspoons lemon juice, 1 teaspoon olive oil, and 1 teaspoon Italian seasoning. Add 1 pound of chicken breast (sliced or cubed) and marinate for at least 30 minutes (or up to 2 hours in the refrigerator).
  2. Prepare bruschetta topping: (Add recipe for bruschetta here - e.g., Combine diced tomatoes, chopped basil, minced garlic, balsamic glaze, salt, and pepper).
  3. Cook pasta: Cook 1 pound penne pasta according to package directions. Drain and set aside.
  4. Sauté vegetables: While pasta cooks, heat 2 teaspoons olive oil in a large skillet over medium-high heat. Add 8 ounces sliced mushrooms and 1/2 cup sliced onions. Cook until softened, about 5-7 minutes.
  5. Make the sauce: Stir in 1 (24-ounce) jar of alfredo sauce into the skillet with the vegetables.
  6. Cook chicken: If using raw chicken, heat a grill pan or skillet over medium heat. Cook marinated chicken until cooked through (internal temperature of 165°F). If using pre-cooked chicken, skip this step.
  7. Combine: Add the cooked pasta to the skillet with the alfredo sauce and vegetables.
  8. Add chicken: Slice the cooked chicken into bite-sized pieces and add to the skillet.
  9. Add cheese: Stir in 1/2 cup shredded Parmesan cheese, 1/2 cup shredded mozzarella cheese, and 1/4 cup shredded Asiago cheese. Cook until cheese is melted and sauce is bubbly.
  10. Serve: Divide pasta among bowls. Top with bruschetta mixture and serve immediately with garlic bread.

Chef's Tip for Extra Flavor

Small additions can make a big impact! Try a sprinkle of fresh herbs, a dash of your favorite spice blend, or a squeeze of citrus just before serving to really enhance the flavors of your dish.

Nutrition Information (Approximate per serving)

Sodium

27 g

Sugar

6g

Fat

54g

Carbs

16g

Recipe Categories (Choose a category and find related recipes!)