Beef Penne Pasta Casserole Recipe

This hearty and comforting Beef Penne Pasta Casserole is a guaranteed family favorite! Tender beef, perfectly cooked penne pasta, and a rich, cheesy sauce baked to bubbly perfection. Easy to make and always a crowd-pleaser, this recipe is perfect for a weeknight dinner or a casual weekend gathering.

Prep Time 20 mins
Cook Time 50 mins
Calories 812.9 kcal
Protein 75g
Rating 3.7 (3 Reviews)
Beef Penne Pasta Casserole

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Recipe Author

Chef Forktionary, author of this recipe

Passionate home cook & Forktionary contributor.

Ingredients for Beef Penne Pasta Casserole

  • Dry Penne Pasta
  • Lean Ground Beef
  • 1 medium onion, chopped
  • 1 (28 ounce) can crushed tomatoes
  • 2 tablespoons tomato paste
  • Red Wine
  • Instant Beef Bouillon
  • Monterey Jack Cheese

How to Make Beef Penne Pasta Casserole

  1. Preheat oven to 350°F (175°C).
  2. In a large saucepan, brown 1 lb ground beef and 1 medium onion (chopped) over medium-high heat, breaking up the beef with a spoon. Drain off any excess grease.
  3. Stir in 1 (28 ounce) can crushed tomatoes, 2 tablespoons tomato paste, 1/2 cup dry red wine (optional), and 2 beef bouillon cubes (crumbled).
  4. Bring to a simmer, reduce heat to low, and cook for 15-20 minutes, stirring occasionally, until the sauce has thickened slightly.
  5. Meanwhile, cook 1 lb penne pasta according to package directions. Drain and set aside.
  6. In a large 13x9 inch baking dish, layer half of the cooked pasta, half of the beef sauce, and half of 2 cups shredded mozzarella cheese.
  7. Repeat layers with remaining pasta, sauce, and cheese.
  8. Cover the baking dish with foil and bake for 20-25 minutes, or until heated through and the cheese is melted and bubbly. Remove foil during the last 5 minutes to brown the top slightly.

Chef's Tip for Extra Flavor

Elevate your dish with simple flavor boosters! A final flourish of freshly chopped herbs can add incredible brightness, while a squeeze of lemon or lime juice right before serving can awaken all the flavors. Don't underestimate a sprinkle of quality finishing salt or a drizzle of good olive oil to make your creation shine.

Nutrition Information (Approximate per serving)

Sodium

43 g

Sugar

46g

Fat

67g

Carbs

36g