Baked Manicotti With Pepperoni Meat Sauce Recipe

Craving a comforting, cheesy, and incredibly flavorful dinner? This Baked Manicotti with Pepperoni Meat Sauce recipe is your answer! Using convenient no-boil lasagna noodles, this recipe is surprisingly quick and easy, perfect for busy weeknights. Adapted from Cook's Country TV and perfected for family enjoyment, this dish is guaranteed to become a new family favorite. Get ready for a taste of pure Italian-American deliciousness!

Prep Time 20 mins

Cook Time 75 mins

Calories 509 kcal

Protein 66g

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Baked Manicotti With Pepperoni Meat Sauce

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The Forktionary Kitchen Team

Adapted from Food.com, then tested & standardized by Forktionary.

Ingredients for Baked Manicotti With Pepperoni Meat Sauce

1 1/2 cups sliced pepperoni
1 lb lean ground beef
1 onion, chopped
2 garlic cloves, minced
Italian Seasoning
1/4 tsp crushed red pepper flakes
Spaghetti Sauce
1/2 tsp salt and 1/4 tsp pepper
15 oz ricotta cheese
Italian Cheese Blend
Provolone Cheese
1 egg
No Boil Lasagna Noodles
1/4 cup grated Parmesan cheese
1 lb Italian sausage
2 (14 1/2 ounce) cans crushed tomatoes
1 (6 ounce) can tomato paste
1 (15 ounce) can tomato sauce
1 tsp dried oregano
1 tsp dried basil
2 cups shredded mozzarella cheese
10 manicotti shells, uncooked

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How to Make Baked Manicotti With Pepperoni Meat Sauce

Preheat oven to 375°F (190°C).
Brown the ground beef and Italian sausage in a large skillet over medium-high heat, breaking it up with a spoon. Drain off any excess grease.
Add the onion and garlic to the skillet and cook until softened, about 5 minutes.
Stir in the crushed tomatoes, tomato paste, tomato sauce, pepperoni, oregano, basil, salt, and pepper. Bring to a simmer and cook for 15 minutes, stirring occasionally.
Meanwhile, lightly grease a 9x13 inch baking dish.
Spread a thin layer of meat sauce in the bottom of the baking dish.
Lay out the lasagna noodles slightly overlapping if necessary to cover the bottom of the baking dish.
Spread half of the remaining meat sauce over the noodles.
Dollop spoonfuls of ricotta cheese mixture over the meat sauce.
Top with the remaining meat sauce and sprinkle with mozzarella cheese.
Bake for 30-35 minutes, or until the cheese is melted and bubbly and the sauce is heated through.
Let stand for 10 minutes before serving.

Nutrition Information (Approximate per serving)

Sodium

46 g

Sugar

35g

Fat

77g

Carbs

Recipe Categories (Choose a category and find related recipes!)

Main Courses Main Dish / Dinner Beef & Red Meat Ground Beef Recipes Pork Recipes European Italian American Baking

Recipe Tags (Choose a tag and find related recipes!)

Time To Make Course Cuisine Preparation Casseroles Main Dish Easy European Italian One Dish Meal 4 Hours Or Less

Frequently Asked Questions

How long does it take to make Baked Manicotti With Pepperoni Meat Sauce?

Baked Manicotti With Pepperoni Meat Sauce takes about 95 minutes from start to finish — roughly 20 minutes to prepare and 75 minutes to cook.

How many calories are in Baked Manicotti With Pepperoni Meat Sauce?

Baked Manicotti With Pepperoni Meat Sauce has approximately 509 calories per serving, with about 66 g protein, 5 g carbohydrates and 51 g fat.

What ingredients do I need for Baked Manicotti With Pepperoni Meat Sauce?

The key ingredients for Baked Manicotti With Pepperoni Meat Sauce are Pepperoni, Lean Ground Beef, Onion, Garlic Cloves, Italian Seasoning, Crushed Red Pepper Flakes. See the full list with measurements above.